Humanin (10mg)

Humanin is a 24-amino-acid peptide encoded inside the mitochondrial genome — one of the small family of mitochondrial-derived signalling peptides that includes MOTS-c. It acts as a cytoprotective and metabolic regulator, defending cells against oxidative stress, apoptosis and amyloid-induced toxicity. Plasma humanin levels decline with age and are altered in type-2 diabetes and Alzheimer's disease, suggesting a key role in metabolic, neuroprotective and longevity signalling. Researched outcomes include improved insulin sensitivity, neuronal survival under stress, cardioprotection in ischemia models and modulation of mitochondrial unfolded protein response. Of interest for users layering metabolic and cognitive longevity tools. Often stacked alongside SS-31 and MOTS-c. Typically dosed 2–3× per week in 8–12 week cycles.