MOTS-c (10mg)

MOTS-c is a 16-amino-acid peptide encoded inside the mitochondrial genome — one of the very few peptides the mitochondria themselves produce as a signalling molecule. It acts as a 'master regulator' of metabolic homeostasis, activating AMPK, increasing insulin sensitivity, driving mitochondrial biogenesis and shifting muscle toward oxidative fiber phenotypes. Human work shows declining MOTS-c levels with age, obesity and type-2 diabetes, and exercise transiently raises circulating MOTS-c. Researched outcomes include improved exercise capacity, fat oxidation, glucose handling and cellular stress resistance — effects that overlap heavily with what endurance training produces at the molecular level. Often paired with SS-31 (membrane repair) and NAD+ (redox currency) in the Mito Stack. Typically dosed 2–3× per week in 8–12 week blocks.